The following is a timeline of the human genome project derived from Nature, 15 February, 2001.

1.  The idea of sequencing the entire human genome was first proposed in discussions
     at scientific meetings organized by the US Department of Energy and others from
     1984 to 1986.

2.  Through 1995, work progressed rapidly on two fronts:
     a.  The first was construction of genetic and physical maps of the human and
          mouse genomes, providing key tools for identification of disease genes and
          anchoring points for genomic sequence.
     b.  The second was sequencing of the yeast and worm genomes, as well as
          targeted regions of mammalian genomes.

3.  Pilot projects were launched to demonstrate the feasibility of cost-effective,
     large-scale sequencing, with a target completion date of March 1999. The projects
     successfully produced finished sequence with 99.99% accuracy and no gaps. They
     also introduced bacterial artificial chromosomes (BACs), a new large-insert
     cloning system that proved to be more stable than the cosmids and yeast artificial
     chromosomes (YACs) that had been used previously.

4.  The second sequence production phase is now under way. Its aims are to achieve
     full-shotgun coverage of the existing clones during 2001, to obtain clones to fill the
     remaining gaps in the physical map, and to produce a finished sequence (apart
     from regions that cannot be cloned or sequenced with currently available
     techniques) no later than 2003.