Chapter 7: Applying DNA Science to Human Genetics

History
Recent Findings

Constructing Maps of the Human Genome

Sequence-tagged Sites and the Polymerase Chain Reaction

Pulse-field and Field-inversion Electrophoresis

Cloning into Yeast Artificial Chromosome

Collecting and Analyzing DNA Sequences

Parallel Sequencing Projects

Human Genetics

Reverse Genetics

DNA Polymorphisms and RFLPs

Using RFLP markers to Map the Huntington's Disease Gene

Cloning the Disease Gene: Chromosome Walking

Cloning the Cystic Fibrosis Gene

DNA Diagnosis

Gene Therapy

DNA Fingerprinting

Table of Contents