Hunt Morgan established the use of Drosophila melanogaster
as the model organism for research in genetics, due to its short generation
time and ease of culturing. He and his students, Alfred
Sturtevant, Calvin Bridges, and Hermann
Muller would be the first to demonstrate sex-linked
inheritance, gene linkage, build the first gene map, and use the frequency
of crossing over as an indicator of distance between genes on chromosomes.